The safety and efficacy of interstitial 125I seed implantation brachytherapy for metastatic epidural spinal cord compression

Treatment of metastatic epidural spinal cord compression: the Goldilocks principle.

Metastatic Epidural Spinal Cord Compression: An Update of Best Practice

The Spine Instability Neoplastic Score SINS is a very important tool; it helps clinicians in identifying when patients with neoplastic disease of the spine should benefit from surgical consultation [2]. The treatment strategy algorithm of Paton et al. [3](LMNOP), evaluates the number of spinal Levels involved and the Location of disease in the spine (L), Mechanical instability (M), Neurology (N...

Continuous Cervical Epidural Analgesia in Metastatic Spinal Cord Compression

Metastatic spinal cord compression is a devastating complication of cancer. Patients may often require high doses of opioids that may cause side effects, myoclonus being one such. A 63-year-old male suffering from malignant spinal cord compression was admitted to our institution. The primary team managed him conservatively with pharmacotherapy with no relief of pain, and he experienced myoclonu...

Metastatic Spinal Cord Compression

According to recent Canadian statistics, an estimated 186,400 new cases of cancer and 75,700 deaths from cancer are expected in Canada in 20121. In general, between 40% and 70% of patients with advanced solid tumours such as those of breast, prostate, and lung will develop bone metastases2. The spine is the most common site for bone metastasis, affecting up to 30% of cancer patients3. Overall, ...

CT-Guided 125I Seed Interstitial Brachytherapy as a Salvage Treatment for Recurrent Spinal Metastases after External Beam Radiotherapy

The aim of this study is to evaluate the feasibility, safety, and clinical efficacy of CT-guided 125I seed interstitial brachytherapy in patients with recurrent spinal metastases after external beam radiotherapy (EBRT). Between August 2003 and September 2015, 26 spinal metastatic lesions (24 patients) were reirradiated by this salvage therapy modality. Treatment for all patients was preplanned ...